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Hidradenitis suppirativa HS vitamin D deficiency

Prevalence of low vitamin D levels in patients with Hidradenitis suppurativa in Jordan: A comparative cross-sectional study


Abstract

Hidradenitis suppurativa (HS) is a chronic inflammatory disease of the apocrine gland bearing skin, presenting various stages of flexural skin pain, erythema, painful nodules, abscesses, sinuses, and fistulas. We aimed to assess serum vitamin D levels in patients with (HS) in Jordan. a cross-sectional comparative study conducted among 110 patients with HS and 110 matched controls, who didn't previously receive vitamin D therapy. Serum vitamin D was measured and classified into normal (>30 ng/ml), insufficient (20-30 ng/ml), and low (<20 ng/ml). The mean age of the cases was 43.1 ± 12.9 years and the mean disease duration was 19.4 months. The mean body mass index among patients with HS was 30 and about 34% of them were smokers. The mean Vitamin D level was 8.4 ng/ml and all HS patients were vitamin D deficient. Patients of HS were more likely to have vitamin D deficiency compared to healthy controls. Most of the study subjects and particularly all of the patients with HS have low vitamin D levels. Smoking and high BMI, were associated with HS. We suggest the implementation standard public dietary recommendations of Vitamin D supplementation, smoking cessation, and weight reduction behaviors with further assessment of disease course among HS patients.


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How much Vitamin D do you need?

VitD3 explanation

Vitamin D adequacy is best determined by measurement of the 25-hydroxyvitamin D concentration in the blood.

Disease Control and Prevention has reported that the percentage of adults achieving vitamin D sufficiency as defined by 25(OH)D of at least 30 ng/mL.

Evidence says an optimal range of 60-100ng/ml.

This is range I use for my patients. Recheck every 3 months until you establish 60+ng/ml. Symptom improvement will occur over a 30-45 day period. I also encourage patients to take a high quality multivitamin and avoid excessive sugar while using natural fats [Butter,Olive oil and Coconut oil. Avoid Omega 6 oils [see blog post on Fats/Oils.]





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